| 7/2/2008 |
Tuberculin skin test can interfere with interferon-gamma assay
|
| NEW YORK (Reuters Health) - The accuracy of a relatively new interferon-gamma (IFN-gamma) assay in detecting latent tuberculosis infection can be compromised if a tuberculin skin test (TST) is used several weeks before, according to a study by South Korea... |
| Source: Chest 2008;133:1415-1420. |
 |
|
|
| 7/2/2008 |
Statin plus bisphosphonate slows premature aging in mouse model of progeria
|
| NEW YORK (Reuters Health) - Combined treatment with pravastatin and zoledronate reverses the signs of premature aging and prolongs survival in a murine model of progeria, scientists in Spain and France report in the June 29 advance online issue of Nature ... |
| Source: Nat Med 2008. |
|
|
|
| 7/1/2008 |
Radioimmunotherapy targets metastatic melanoma lesions in phase I trial
|
| NEW YORK (Reuters Health) - Promising findings from a phase I clinical trial indicate that melanin-binding monoclonal antibody labeled with rhenium-118 safely and effectively targets metastatic melanoma soft tissue lesions, investigators reported at the S... |
| Source: |
|
|
|
| 6/26/2008 |
Angiotensin-converting enzyme inhibitors increase angioedema risk
|
| NEW YORK (Reuters Health) - The risk of angioedema is more than 3 times higher with angiotensin-converting enzyme (ACE) inhibitors than with other antihypertensive drugs, according to a report in the June issue of Hypertension.While angioedema associated ... |
| Source: Hypertension 2008;51:1465-1467,1624-1630. |
|
|
|
| 6/24/2008 |
NSAIDs offer no protection against melanoma
|
| NEW YORK (Reuters Health) - Despite laboratory evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) could play a role in prevention of melanoma, a prospective observational study failed to find any evidence in support of such an association.Dr. Mar... |
| Source: J Natl Cancer Inst 2008. |
|
|
|
| 6/23/2008 |
Intermittent tacrolimus ointment therapy helps prevent relapse of stabilized atopic dermatitis
|
| NEW YORK (Reuters Health) - In patients with stabilized atopic dermatitis, intermittent therapy with tacrolimus ointment was associated with significantly more flare-free days and longer time to first relapse compared with vehicle alone, according to a re... |
| Source: J Am Acad Dermatol 2008;58:990-999. |
|
|
|
| 6/20/2008 |
KINK-1 increases melanoma sensitivity to chemotherapy
|
| NEW YORK (Reuters Health) - KINK-1, a kinase inhibitor of nuclear factor kappa B (NFkB), increases the susceptibility of melanoma cells to antitumoral treatment, scientists from Germany report in the June 18th issue of the Journal of the National Cancer I... |
| Source: J Natl Cancer Inst 2008;100:862-875,833-835. |
|
|
|
| 6/18/2008 |
U.S. panel backs proposed J&J psoriasis drug
|
| SILVER SPRING, Md., (Reuters) - An experimental Johnson & Johnson drug should be approved for treating adults with moderate or severe psoriasis, a advisory panel unanimously ruled Tuesday.The ability of the drug, ustekinumab, to relieve symptoms of th... |
| Source: |
|
|
|
| 6/16/2008 |
Amniotic membranes rapidly reverse skin detachment caused by epidermal necrolysis
|
| NEW YORK (Reuters Health) - In a case report of a woman with lamotrigine-induced toxic epidermal necrolysis (TEN), placement of amniotic membranes over areas of epidermal detachment led to complete re-epithelialization within 5 days.Reporting in the June ... |
| Source: Arch Dermatol 2008;144:724-726. |
|
|
|
| 6/16/2008 |
New test may improve detection of latent TB in rheumatoid arthritis
|
| NEW YORK (Reuters Health) - A test that measures interferon-gamma release in response to bacterial antigens is more accurate than skin tests in detecting latent tuberculosis infection in patients with rheumatoid arthritis, new research shows. However, a ... |
| Source: J Rheumatol 2008;35:770-781. |
|
|
|
| 6/16/2008 |
Cosmetic surgery booming in Britain, study finds
|
| LONDON (Reuters) - Britons might be feeling the pinch of the global credit crunch, but they're still ready to pay thousands of pounds for cosmetic surgery, a report suggested on Monday.Britain's largest cosmetic surgery provider the Harley Medical Group s... |
| Source: |
|
|
|
| 6/16/2008 |
Amgen's Enbrel in kids 'concerning,' FDA staff says
|
| WASHINGTON (Reuters) - U.S. drug regulators are concerned about life-threatening complications in children taking Amgen Inc's drug Enbrel for psoriasis and other conditions, according to documents released on Monday.Amgen, which markets the injectable dru... |
| Source: |
|
|
|
| 6/13/2008 |
Telavancin effective for treating complicated skin infections
|
| NEW YORK (Reuters Health) - Telavancin is at least as effective as vancomycin for treating complicated skin and skin-structure infections (SSSI), according to a report in the June 1st Clinical Infectious Diseases.Telavancin, an investigational lipoglycope... |
| Source: Clin Infect Dis 2008;46:1683-1693. |
|
|
|
| 6/13/2008 |
Hair dye may increase the risk of non-Hodgkin lymphoma
|
| NEW YORK (Reuters Health) - Use of hair dye may increase the risk of certain types of non-Hodgkin lymphoma (NHL), according to a report in the June 1st American Journal of Epidemiology.Personal use of hair dye has been suggested as a risk factor for NHL, ... |
| Source: Am J Epidemiol 2008;167:1321-1331. |
|
|
|
| 6/13/2008 |
US FDA staff sees risks with investigational psoriasis drug
|
| WASHINGTON (Reuters) - An experimental psoriasis drug from Johnson & Johnson was effective in clinical trials, but long-term use may increase the risk of cancer, U.S. drug reviewers said in documents released on Friday."Long-term use of ustekinumab ma... |
| Source: |
|
|
|
| 6/12/2008 |
High melanoma incidence seen in methotrexate-treated rheumatoid arthritis
|
| NEW YORK (Reuters Health) - Patients with rheumatoid arthritis (RA) treated with methotrexate appear to be at elevated risk of melanoma compared with the general population, according to an Australian cohort study reported in the June 15 issue of Arthriti... |
| Source: Arthritis Rheum 2008;59:794-799. |
|
|
|
| 6/11/2008 |
Intestinal bacterial overgrowth contributes to systemic sclerosis symptoms
|
| NEW YORK (Reuters Health) - Small intestinal bacterial overgrowth (SIBO) is common and contributes to symptoms in patients with systemic sclerosis, according to a report in the May issue of the American Journal of Gastroenterology."Gastrointestinal sympto... |
| Source: Am J Gastroenterol 2008;103:1257-1262. |
|
|
|
| 6/9/2008 |
Tumor suppressor ARF inactivated in human melanoma
|
| NEW YORK (Reuters Health) - The tumor suppressor p14ARF (ARF) is commonly inactivated in human melanoma cell lines and melanoma metastases, according to a report in the June 4th issue of the Journal of the National Cancer Institute."The prevailing dogma, ... |
| Source: J Natl Cancer Inst 2008;100:784-795,757-759. |
|
|
|
| 6/4/2008 |
Laryngeal papilloma relapse treatable with intralesional cidofovir
|
| NEW YORK (Reuters Health) - A team that previously reported that laryngeal papilloma responds well to intralesional cidofovir is now reporting that another round of the nucleoside analogue can be effective if the disease relapses.Principal investigator Dr... |
| Source: Arch Otolaryngol Head Neck Surg 2008;134:497-500. |
|
|
|
| 6/2/2008 |
Mutations affecting telomerase implicated in premature aging syndrome
|
| NEW YORK (Reuters Health) - Mutations leading to the premature aging syndrome dyskeratosis congenita are associated with low blood levels of telomerase RNA, confirming the underlying role of shortened telomeres in the condition, according to a report in P... |
| Source: Proc Natl Acad Sci USA 2008. |
|
|
|
| 5/30/2008 |
Interferon benefits patients with early stage III melanoma
|
| NEW YORK (Reuters Health) - Adjuvant treatment with high-dose interferon improves recurrence-free survival in patients with early stage IIIA melanoma, researchers from Houston, Texas report.Previous randomized trials, in the "pre-sentinel lymph node biops... |
| Source: Cancer 2008;112:2030-2037. |
|
|
|
| 5/30/2008 |
TB "pseudoepidemics" common in US armed forces
|
| NEW YORK (Reuters Health) - High rates of false-positive tuberculin skin test (TST) conversions are common among US Army personnel, particularly after overseas deployments, investigators report in the June issue of the American Journal of Respiratory and ... |
| Source: Am J Respir Crit Care Med 2008;177:1285-1289. |
|
|
|
| 5/28/2008 |
Proactive treatment with tacrolimus controls atopic dermatitis
|
| NEW YORK (Reuters Health) - "Proactive" long-term treatment with twice-weekly topical tacrolimus safely reduces disease exacerbations in patients with atopic dermatitis, members of the European Tacrolimus Ointment Study Group report in the June issue of A... |
| Source: Allergy 2008;63:742-750. |
|
|
|
| 5/27/2008 |
C1-inhibitor therapy effective for hereditary angioedema
|
| NEW YORK (Reuters Health) - Injection of C1-inhibitor concentrate can reduce the skin swelling in patients with hereditary angioedema, German researchers report in the June issue of Allergy.Dr. Konrad Bork of Johannes Gutenberg University, Mainz and colle... |
| Source: Allergy 2008;63:751-757. |
|
|
|
| 5/27/2008 |
Custom therapeutic insoles enhance forefoot pressure relief
|
| NEW YORK (Reuters Health) - Custom therapeutic insoles enhance plantar pressure relief in high-pressure areas under the forefoot, according to a report in the May issue of Diabetes Care."Not all insoles are equal," Dr. Georgeanne Botek from Cleveland Clin... |
| Source: Diabetes Care 2008;31:839-844. |
|
|
|